Most people searching for the best sleep medication reach for Benadryl or another OTC option without realizing these drugs carry cumulative anticholinergic risks linked to cognitive decline over time. Ultra-low-dose doxepin, FDA-approved at 3 mg and 6 mg, works through an entirely different mechanism and may be the best sleep medication option for adults concerned about those risks.

A take-home sleep study measures breathing, oxygen, heart rate, and more to check for conditions like sleep apnea. It can’t diagnose insomnia or narcolepsy, but it’s a convenient way to gather real-world data. Unless directed otherwise, continue your usual sleep medications so the study reflects your typical night—and aim for at least two nights of testing for the clearest picture.